This multi-centre international prospective observational study will improve our understanding of NIRS/EEG patterns and effects of sedation and anaesthesia on brain activity in infants undergoing neonatal surgery.
Prior work by this group, funded by ANZCA, has demonstrated that many infants undergoing anaesthesia show periods of isoelectricity, suggesting a very deep degree of anaesthesia.
This follow-up project focusses on neonates undergoing significant surgery and will add cerebral oximetry measurements to better understand the neurocirculatory and electroencephalographic effects of anaesthesia and surgery on the developing brain, including the postoperative period in the neonatal intensive care unit.
Associate Professor Justin Skowno, Dr Reza Kahlaee, Children’s Hospital at Westmead, NSW;
Associate Professor Neil Hauser, Perth Children’s Hospital, Western Australia;
Associate Professor Yuan, Children’s Hospital of Philadelphia, USA
The project was awarded A$69,806 funding through the ANZCA research grants program for 2024.