Propofol anaphylaxis

ANZCA has been notified of an episode of life-threatening anaphylaxis, most likely triggered by propofol, in a previously well 12 year-old boy with no allergy history. Propofol anaphylaxis is extremely rare but possible.

The anaphylaxis episode may have been prolonged by propofol use for sedation during interhospital transfer and initial time in ICU. Assuringly, the patient made a full recovery. 

The case has been referred to our Perioperative Allergy Sub-committee to consider and was discussed at the October meeting of the Safety and Quality Committee. Further details of this case will be published in the Summer edition of the ANZCA Bulletin.